Medusa was Sally's biological mother and the second wife of Papa Acachalla (who was her second husband). Sally's father (Medusa's first husband) used to constantly make phone calls to Medusa about Sally. One phone call was about how Sally probably had brain damage, Sally commented on the call, but her father lied to her and said that she has "bran cereal". Darth Calculus kidnapped Sally and killed Medusa in order to get more customers in his hotel.
- Medusa has not met Billy nor Gertrude and is most likely not aware either.
- She likes cheese.
- She may the woman Papa strapped to the top of his car, mentioned in the Papa Acachalla Town Roleplay Map video.
- She was mentioned as being Papa Acachalla's first love, in the Disney Haunted Mansion video but was revealed to have been his second wife after Cleopatra, possibly meaning he left Cleopatra for her.